Bibliografia

 

1.  Fried LP, Tangen CM, Walston J et al. Frailty in older adults: evidence for a pheno-type. J Gerontol A Biol Sci Med Sci 2001;56: M146–56.
2.  Perera V, Bajorek BV, Matthews S, Hilmer SN. The impact of frailty on the utilisation of antithrombotic therapy in older patients with atrial fibrillation. Age Ageing 2009;38:156–62.
3.  Alboni P, Stucci N, Cojocaru E, Ungar A. Efficacy and safety of oral anticoagulants in frail elderly patients with atrial fibrillation: an unsolved problem. G Ital Cardiol (Rome) 2017 Mar;18:180-187.
4.  Granziera S, Bertozzo G, Pengo V et al. To treat or not to treat very elderly naïve patients with atrial fibrillation with vitamin K antagonists (VKA): results from the VENPAF cohort. Intern Emerg Med 2015 Oct;10(7):795-804.
5.  Kooistra HA, Calf AH, Piersma-Wichers M et al. Risk of Bleeding and Thrombosis in Patients 70 Years or Older Using Vitamin K Antagonists. JAMA Intern Med 2016 Aug 1;176:1176-83.
6.  Halperin JL, Hankey GJ, Wojdyla DM et al; ROCKET AF Steering Committee and Investigators. Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF). Circulation. 2014 Jul 8;130(2):138-46.
7.  Kirchhof P, Benussi S, Kotecha D et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J 2016 Oct 7;37:2893-2962. Epub 2016 Aug 27.
8.  Man-Son-Hing M, Nichol G, Lau A, Laupacis A. Choosing antithrombotic therapy for elderly patients with atrial fibrillation who are at risk for falls. Arch Intern Med 1999 Apr 12;159(7):677-85.
9.  Donzé J, Clair C, Hug B et al. Risk of falls and major bleeds in patients on oral anticoagulation therapy. Am J Med 2012 Aug;125:773-8.
10.  Andreotti F et al. Antithrombotic therapy in the elderly: expert position paper of the European Society of Cardiology Working Group on Thrombosis. Eur Heart J 2015;36:3238-49.
11.  Ruff CT, Giugliano RP, Braunwald E et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet 2014 Mar 15;383(9921):955-62.
12.  Prins MH, Lensing AW, Bauersachs R et al; EINSTEIN Investigators. Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN-DVT and PE randomized studies. Thromb J 2013 Sep 20;11:21.
13.  Geldhof V, Vandenbriele C, Verhamme P, Vanassche T. Venous thromboembolism in the elderly: efficacy and safety of non-VKA oral anticoagulants. Thromb J 2014 Oct 13;12:21.

 

 

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