Bibliografia

 

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14) Huang WJ, Shu CH, Chou KT et al. Evaluating the Autonomic Nervous System in Patients with Laryngopharyngeal Reflux. Otolaryngol Head Neck Surg 2013; 148(6):997-1002.

15) De Benedetto M, Monaco G, Marra F. Extra-laryngeal manifestations of gastro-oesophageal reflux. Acta Otorhinolaryngol Ital 2006; 26(5):256-9.

16)  Johnston N, Knight J, Dettmar PW et al. Pepsin and carbonic anhydrase isoenzyme III as diagnostic markers for laryngopharyngeal reflux disease. Laryngoscope 2004; 114:2129-34.

17) Johnston N, Bulmer D, Gill GA. Cell biology of laryngeal epithelial defenses in health and disease: further studies. Ann Otol Rhinol Laryngol 2003; 112:481-91.

18) Helm JF, Dodds WJ, Pelc LR et al. Effect of esophageal emptying and saliva on clearance of acid from the esophagus. N Engl J Med 1984; 310(5):284-8.

19) Yandrapu H, Marcinkiewicz M, Poplawski C et al. Role of saliva in esophageal defense: implications in patients with nonerosive reflux disease. Am J Med Sci 2015; 349(5):385-91.

20) Eckley CA, Michelsohn N, Rizzo LV et al. Salivary epidermal growth factor concentration in adults with reflux laryngitis. Otolaryngol Head Neck Surg 2004 Oct;131(4):401-6. Erratum in: Otolaryngol Head Neck Surg 2005; 132(2):344.

21) Orlando RC. Reflux esophagitis. In: Yamada T, Alpers DH, Laine L, Owyang C,

Powell DW, eds. Textbook of Gastroenterology. Philadelphia: Lippincott Williams & Wilkins, 1999; 1235-1263

22) Koufman JA, Aviv JE, Cassiano RR et al. Laryngopharyngeal reflux: position statement of the committee on speech, voice, and swallowing disorders of the American Academy of Otolaryngology-Head and Neck Surgery. Otolaryngol Head and Neck Surg 2002; 127:32-35.

23) Johnston N, Knight J, Dettmar PW et al. Pepsin and carbonic anhydrase isoenzyme III as diagnostic markers for laryngopharyngeal reflux disease. Laryngoscope 2004; 114:2129-2134.

24) Johnston N, Bulmer D, Gill GA et Al. Cell biology of laryngeal epithelial defenses in health and disease: further studies. Ann Otol Rhinol Laryngol 2003; 112:481-491.

25) Reichel O, Mayr D, Durst F et al. E-cadherin but not beta-catenin expression is decreased in laryngeal biopsies from patients with laryngopharyngeal reflux. Eur Arch Otorhinolaryngol 2008; 265:937-42.

26) Johnston N, Wells CW, Samuels TL et al. Pepsin in nonacidic refluxate can damage hypopharyngeal epithelial cells. Ann Otol Rhinol Laryngol 2009; 118:677-85.

27) Shimazu R, Kusano K, Kuratomi Y et al. Histological changes of the pharynx and larynx in rats with chronic acid reflux esophagitis. Acta Otolaryngol 2009; 129(8):886-92.

 28) Johnston N, Dettmar PW, Lively MO et al. Effect of pepsin on laryngeal stress protein (Sep70, Sep53, and Hsp70) response: role in laryngopharyngeal reflux disease. Ann Otol Rhinol Laryngol 2006; 115(1):47-58.

29) Johnston N, Wells CW, Blumin JH et al. Receptor-mediated uptake of pepsin by laryngeal epithelial cells. Ann Otol Rhinol Laryngol 2007; 116(12):934-8.

30) Shimazu R, Kusano K, Kuratomi Y et al. Histological changes of the pharynx and larynx in rats with chronic acid reflux esophagitis. Acta Otolaryngol 2009; 129(8):886-92.

31) Savarino E, Zentilin P, Tutuian R et al. The role of nonacid reflux in NERD: lessons learned from impedance-pH monitoring in 150 patients off therapy. Am J Gastroenterol 2008; 103:2685-93.

32) Johnston N, Wells CW, Samuels TL et al. Rationale for targeting pepsin in the treatment of reflux disease. Ann Otol Rhinol Laryngol 2010; 119(8):547-58.

33) Lee AL, Button BM, Denehy L et al. Exhaled Breath Condensate Pepsin: Potential Noninvasive Test for Gastroesophageal Reflux in COPD and Bronchiectasis. Respir Care 2015; 60(2):244-50.

34) Krishnan U, Paul S, Messina I et al. Correlation between laryngobronchoscopy and pepsin in the diagnosis of extra-oesophageal reflux. J Laryngol Otol 2015; 129(6):572-9.

35) Luo H, Gao Y, Ma S et al. [The expression and clinical significance of pepsin and pepsinogen in patients with otitis media with effusion].[Article in Chinese] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2015; 29(14):1252-5.

36) Ren J, Zhao Y, Ren X. [An association between adenoid hypertrophy and extra-gastroesophageal reflux disease].[Article in Chinese] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2015; 29(15):1406-8.

37) Meyer KC. Gastroesophageal reflux and lung disease. Expert Rev Respir Med 2015; 9(4):383-5.

38) Spyridoulias A, Lillie S, Vyas A et al. Detecting laryngopharyngeal reflux in patients with upper airways symptoms: Symptoms, signs or salivary pepsin? Respir Med 2015; 109(8):963-9.

39) Southwood JE, Hoekzema CR, Samuels TL et al. The Impact of Pepsin on Human Nasal Epithelial Cells In Vitro: A Potential Mechanism for Extraesophageal Reflux Induced Chronic Rhinosinusitis. Ann Otol Rhinol Laryngol 2015; 124(12):957-64.

40) Iannella G, Di Nardo G, Plateroti R et al. Investigation of pepsin in tears of children with laryngopharyngeal reflux disease. Int J Pediatr Otorhinolaryngol 2015; 79(12):2312-5

41) Na SY, Kwon OE, Lee YC et al. Optimal timing of saliva collection to detect pepsin in patients with laryngopharyngeal reflux. Laryngoscope 2016; 14.

42) Kim JH, Jeong HS, Kim KM et al. Extra-Esophageal Pepsin from Stomach Refluxate Promoted Tonsil Hypertrophy. PLoS One 2016; 8:11(4):e0152336.

43) Johnston N, Ondrey F, Rosen R et al. Airway reflux. Ann N Y Acad Sci 2016; 16.

44) Dhillon VK, Akst LM. How to Approach Laryngopharyngeal Reflux: An Otolaryngology Perspective. Curr Gastroenterol Rep 2016; 18(8):44.

45) Ford CN. Evaluation and management of laryngopharyngeal reflux. JAMA 2005; 294:1534-40.

46) Kahrilas PJ, Shaheen NJ, Vaezi MF et al. American Gastroenterological Association Institute technical review on the management of gastroesophageal reflux disease. Gastroenterology 2008; 135(4):1392-1413.

47) Chater PI, Wilcox MD, Brownlee IA et al. Alginate as a protease inhibitor in vitro and in a model gut system; selective inhibition of pepsin but not trypsin. Carbohydr Polym 2015; 131:142-51.

 

 

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